Organic letters

Crotylations of α-Carbonyl Radicals with Crotylstannane

MP Sibi, H Miyabe

Index: Sibi, Mukund P; Miyabe, Hideto Organic letters, 2002 , vol. 4, # 20 p. 3435 - 3438

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Citation Number: 13

Abstract

Electrophilic radicals undergo crotylation with crotylstannane with moderate to good efficiency. The reaction provides the syn isomer as the major product. The present methodology is complementary to Claisen protocols for the synthesis of γ, δ-unsaturated carboxylic acid derivatives. Details of the new radical methodology are presented.