1-Chloro-1, 3-bis (dimethylamino)-2-azapropenylium salts: intermediates for the synthesis of 1, 3, 5-triazines, pyrimidines, isoquinolines, quinazolines, and a 1, 3, 5- …

GV Boyd, PF Lindley, GA Nicolaou

Index: Boyd, Gerhard V.; Lindley, Peter F.; Nicolaou, George A. Journal of the Chemical Society, Chemical Communications, 1984 , # 16 p. 1105 - 1107

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Abstract

The title salts, which are formed by the action of dimethylcyanamide on the phosphorus oxychloride complexes of a variety of tertiary amides, are useful precursors of six-membered heteroaromatic compounds: they react with simple amidines to yield 1, 3, 5-triazines and with N, N-dimethylamidines to give pyrimidines; 3-arylmethyl-1-chloro-1, 3-bis (dimethylamino)-2-azapropenylium perchlorates form isoquinolines, the related 3- ...