Synthesis and spectral properties of 2??[(o??and p??substituted) aminophenyl]??3H??5??[(o??and p??substituted) phenyl]??7??chloro??1, 4??benzodiazepines

…, RS Franco, OG Mellado

Index: Cortes Cortes; Salazar Franco; Garcia Mellado Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 663 - 669

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Citation Number: 10

Abstract

Abstract A series of twelve new 2-[(o-and p-substituted) aminophenyl]-3H-5-[(o-and p- substituted) phenyl]-7-chloro-1, 4-benzodiazepines, which have possible pharmacological properties has been obtained. The synthesis was carried out following six steps. The structure of all products was corroborated by ir, 1 H nmr, 13 C nmr and ms. In addition for the compound 2-(o-chloroaminophenyl)-3H-5-(o-fluorophenyl)-7-chloro-1, 4-benzodiazepine ...