Darstellung „chiraler” α??Aminoisobuttersäure

T Weihrauch, D Leibfritz

Index: Weihrauch, Thomas; Leibfritz, Dieter Liebigs Annalen der Chemie, 1985 , # 9 p. 1917 - 1921

Full Text: HTML

Citation Number: 0

Abstract

Synthesis of “Chiral” a-Aminoisobutyric Acid a-Methylalanine (a-aminoisobutyric acid), a rare naturally occuring achiral amino acid, is an efficient inducer of secondary structure for peptides and easy to characterize by NMR because of its prochiral methyl groups.“Chiral” a- mcthylalanine is enantioselectively synthesized oia the bislactim-ether method where the pro-R-methyl group has three or one deuterium atom (s). or-Aminoisobutterslure (or- ...