Tetrahedron

Polar effects in free-radical reactions. New synthetic developments in the functionalization of heteroaromatic bases by nucleophilic radicals

F Minisci, A Citterio, E Vismara, C Giordano

Index: Minisci, Francesco; Citterio, Attilio; Vismara, Elena; Giordano, Claudio Tetrahedron, 1985 , vol. 41, # 19 p. 4157 - 4170

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Citation Number: 72

Abstract

The synthetic interest of the direct substitution of protonated heteroaromatic bases by nucleophilic carbon-centered radicals is furtheron developed by the following new achievements: i) utilization of the redoc system in several solvents; ii) utilization of benzoyl peroxide in alcohols; iii) carbamoylation by HCONH2 and H2O2 in the presence of catalytic amounts of Fe (II). These systems allow to obtain either substitution till now tried without ...