Macrocyclization via an isomerization reaction at high concentrations promoted by palladium templates

BM Trost, RW Warner

Index: Trost,B.M.; Warner,R.W. Journal of the American Chemical Society, 1982 , vol. 104, p. 6112

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Citation Number: 84

Abstract

The ability to form medium and macrocyclic rings has normally relied upon high dilution to ensure intramolecular vs. intermolecular reactions.'The inefficiency associated with large volumes of solvent, which can be somewhat ameliorated by the use of slow addition techniques, encourages exploration of methodology that avoids high dilution. The principle of “pseudodilution” within cross-linked polymers, 2 which has been so successfully ...