Journal of the American Chemical Society

The Preparation of Some Tertiary Alcohols by the Addition of Organic Acids to Grignard Reagents

RC Huston, DL Bailey

Index: Huston; Bailey Journal of the American Chemical Society, 1946 , vol. 68, p. 1382

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Citation Number: 11

Abstract

(200 ml. per mole of acid), distilling off the ether until the temperature reached 83' and then re- fluxing for two hours. For example, when this ructhod was used, the yield of ~-tiretliyl-:~-ethyl -~~- pentanol was 7096 instead of 53'17,. The addition of the second niolecule of alkyl- niagnesium halide to the salt and subsequent cliiiiinatioii of oxyniagiiesium halide wa ~ relatively slow. Less tlim fifteen per cent. or ketonr was formed from butyric acid and s-butylmagncsiuin ...