Palladium??Catalyzed Intramolecular Nucleophilic Substitution at the Alkoxycarbonyl Group

D Solé, O Serrano

Index: Sole, Daniel; Serrano, Olga Angewandte Chemie - International Edition, 2007 , vol. 46, # 38 p. 7270 - 7272

Full Text: HTML

Citation Number: 30

Abstract

The widespread application of palladium catalysts in organic synthesis owes mainly to their tolerance of most important functional groups, largely as a result of the low nucleophilicity of organopalladium compounds.[1] Thus, aryl and vinyl palladium complexes are commonly used as electrophiles in CÀC coupling reactions, and there are only a few examples of their use as nucleophiles in reactions with polar electrophilic multiple bonds.[2–5] ...