Reactions of protected amino acid chlorides mediated by SmI 2.
J Collin, JL Namy, G Jones, HB Kagan
Index: Collin, J.; Namy, J. L.; Jones, G.; Kagan, H. B. Tetrahedron Letters, 1992 , vol. 33, # 21 p. 2973 - 2976
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Citation Number: 11
Abstract
Abstract Reactions of N-protected amino acid chlorides with carbonyl compounds in the presence of SmI 2 were investigated. Decarbonylation followed by a cross coupling between amino moiety and aldehyde or ketone is observed. By the use of FMOC derivatives, N- protected amino alcohols were isolated in moderate yields.
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