Chinese Journal of Chemistry

Cu2O??Mediated Room Temperature Cyanation of Aryl Boronic Acids/Esters and TMSCN

Y Ye, Y Wang, P Liu, F Han

Index: Ye, Yong; Wang, Yanhua; Liu, Pengtang; Han, Fushe Chinese Journal of Chemistry, 2013 , vol. 31, # 1 p. 27 - 30

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Citation Number: 9

Abstract

Abstract A method for the efficient and reliable synthesis of aryl nitriles via the Cu 2 O- catalyed cross-coupling of aryl boronic acids or esters and TMSCN is presented. A broad range of substrates decorated by electron-rich and deficient, sterically very congested, and labile functionalities were tolerated. Moreover, the reaction can proceed under mild conditions at room temperature. These advantages paired with the use of cheap, readily ...

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