1-(1-Naphthyl) ethylamine and derivatives thereof as chiral modifiers in the enantioselective hydrogenation of ethyl pyruvate over Pt–alumina

…, G Wang, A Pfaltz, B Minder, M Schürch…

Index: Heinz, Thomas; Wang, Guozhi; Pfaltz, Andreas; Minder, Bruno; Schuerch, Markus; et al. Journal of the Chemical Society, Chemical Communications, 1995 , # 14 p. 1421 - 1422

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Citation Number: 58

Abstract

Catalytic quantities of ()-or ()-1-(1-naphthyl) ethylamine induce up to 82% ee in the hydrogenation of ethyl pyruvate over Pt–alumina, the actual modifier responsible for enantioselection being the secondary amine resulting from imine formation with ethyl pyruvate and subsequent reduction of the C [[double bond, length half m-dash]] N bond; a serie