Synlett

A new synthesis of 3-substituted pyrrolidines using iron catalysed cross-coupling reactions and ring closing metathesis

…, BT Pedersen, N Skjaerbaek, P Vedsø, M Begtrup

Index: stergaard, Niels; Thoning Pedersen, Brian; Skjaerbaek, Niels; Vedso, Per; Begtrup, Mikael Synlett, 2002 , # 11 p. 1889 - 1891

Full Text: HTML

Citation Number: 4

Abstract

Abstract A series of 3-substituted N-Boc protected pyrrolidines have been prepared via iron catalysed cross-coupling between Boc protected N-allyl-N-(2-bromoallyl) amine 3 and organomagnesium compounds followed by ring closing metathesis and subsequent hydrogenation of the formed pyrrolines.