Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1, 6, 7-trisubstituted dihydroisoquinolines and isoquinolines

S Batra, YA Sabnis, PJ Rosenthal, MA Avery

Index: Bioorganic and Medicinal Chemistry, , vol. 11, # 10 p. 2293 - 2299

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Citation Number: 60

Abstract

... Bioorganic & Medicinal Chemistry. ... c Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; d Department of Chemistry, PO Box 1848, University of Mississippi ... Therefore, chemo-therapy of malaria remains a challenge to medicinal chemists. ...