A Facile Two-Step Synthesis of 3-Fluoro-6-methoxyquinoline

B Li, Z Zhang, M Mangano

Index: Organic Process Research and Development, , vol. 12, # 6 p. 1273 - 1275

Full Text: HTML

Citation Number: 2

Abstract

... Research-API, Pharmaceutical Sciences, Pfizer ... This process proved to be successful, and dichlorofluoroquinoline 3b was obtained in ∼60% yield. ... The organic layers were combined, dried with sodium sulfate, and concentrated to give the product as a white solid (36.1 g, 99%). ...