Microscopic visualization of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probes

…, J Engelmann, M Goldberg, D Parker

Index: Smith, David G.; Law, Ga-Lai; Murray, Benjamin S.; Pal, Robert; Parker, David; Wong, Ka-Leung Chemical Communications, 2011 , vol. 47, # 26 p. 7347 - 7349

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Citation Number: 10

Abstract

A series of bimodal metabotropic glutamate-receptor targeted MRI contrast agents has been developed and evaluated, based on established competitive metabotropic Glu receptor subtype 5 (mGluR5) antagonists. In order to directly visualize mGluR5 binding of these