Rhodium??Catalyzed Asymmetric Synthesis of Spirocarbocycles: Arylboron Reagents as Surrogates of 1, 2??Dimetalloarenes

R Shintani, S Isobe, M Takeda…

Index: Shintani, Ryo; Isobe, Shingo; Takeda, Momotaro; Hayashi, Tamio Angewandte Chemie - International Edition, 2010 , vol. 49, # 22 p. 3795 - 3798

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Citation Number: 55

Abstract

Enantiopure spirocycles that possess a quaternary spirocarbon stereocenter [1] represent an important class of compounds as they can be found in various useful organic molecules, such as natural products,[2] biologically active compounds,[3] and effective chiral ligands for asymmetric catalysis.[4] Construction of such spirocycles using transitionmetal-catalyzed asymmetric carbon–carbon bond-forming reactions are highly desirable in view of the ...