Tetrahedron letters

Microwave assisted synthesis of an unusual dinitro phytochemical

…, MS Manhas, V Srirajan, A Bhattacharjee, S Rumthao…

Index: Bose, Ajay K.; Ganguly, Subhendu N.; Manhas, Maghar S.; Srirajan, Vaidyanathan; Bhattacharjee, Ashoke; Rumthao, Sochanchingwung; Sharma, Anju H. Tetrahedron Letters, 2004 , vol. 45, # 6 p. 1179 - 1181

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Citation Number: 18

Abstract

A novel dinitro secondary metabolite, 2-nitro-4-(2 ′ -nitroethenyl)phenol has been isolated from a marine source. This metabolite was synthesized first (in 1964 in Japan) and discovered later (in 1991 in India) as a natural product. We describe here a new synthesis via highly accelerated, microwave assisted, nitration reactions using mild reagents. ipso-Substitution of a carboxy group by a nitro group is discussed. ... In the course of a joint Indo-US project 1 ...

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