Tetrahedron

Electrochemical generation of N-(2, 2-dichlorovinyl) amides

A Guirado, R Andreu, A Cerezo, J Gálvez

Index: Guirado, Antonio; Andreu, Raquel; Cerezo, Alfredo; Galvez, Jesus Tetrahedron, 2001 , vol. 57, # 23 p. 4925 - 4931

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Citation Number: 13

Abstract

A convenient method for the synthesis of N-(2, 2-dichlorovinyl) amides has been established. Treatment of chloralamides with phosphorus pentachloride provides N-(1, 2, 2, 2-tetrachloroethyl) amides in high yields whose electrochemical reduction leads to the title compounds in fair to quantitative yields. This approach exhibits superior efficiency and versatility than previously reported procedures.