A Straightforward Synthesis of O-Protected 3-Hydroxypropanal derivatives

D Barbier, JP Salvi, N Walchshofer…

Index: Barbier, Denis; Salvi, Jean-Paul; Walchshofer, Nadia; Paris, Joelle Organic Preparations and Procedures International, 1994 , vol. 26, # 1 p. 121 - 122

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Abstract

Bifunctional compounds like 3-tetrahydropyranyloxypropanal derivatives are very useful intermediates for the synthesis of various prod~ cts. l-~ As part of our research program, we sought a method for the synthesis of compound 2b from ethyl 3.3-diethoxy-2-methyl propanoate 3.4 Herein, we report a convenient method for the one-pot preparation of aldehydes 2 from alcohols 1.

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