Russian journal of organic chemistry

Cyclization of substituted 3, 4-diaminopyridines into 1H-[1, 2, 3] triazolo [4, 5-c] pyridine 2-oxide derivatives during the nitration process

NN Smolyar, AB Vasilechko

Index: Smolyar; Vasilechko Russian Journal of Organic Chemistry, 2010 , vol. 46, # 8 p. 1219 - 1222

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Citation Number: 1

Abstract

Abstract The nitration of pyridine-3, 4-diamine, its N, N′-diacetyl derivative, and N 4- alkylpyridine-3, 4-diamines with excess nitric acid in concentrated sulfuric acid at 60° C was accompanied by cyclization with formation of the corresponding 1-substituted 4-nitro-1 H-[1, 2, 3] triazolo [4, 5-c] pyridine 2-oxides. 4-Chloro-1 H-[1, 2, 3] triazolo [4, 5-c] pyridine 2-oxide derivatives were obtained under analogous conditions from 2-chloropyridine-3, 4-diamine ...