Synthesis and pharmacological properties of some novel pyrazolidine and pyrazole derivatives

B Parashar, A Jain, S Bharadwaj…

Index: Parashar, Bharat; Jain, Abhilasha; Bharadwaj, Sudhir; Sharma Medicinal Chemistry Research, 2012 , vol. 21, # 8 p. 1692 - 1699

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Abstract

Abstract Microwave synthesis technique opens new avenues for the synthesis of many compounds. A novel and simple method has been developed for the synthesis of 1-(2, 4- dinitrophenyl) pyrazolidine-3, 5-dione and 1-(2, 4-dinitrophenyl)-3, 5-dimethyl-1H-pyrazole derivatives under microwave irradiation. These compounds exhibit mild to moderate antimircrobial activity against different strains of bacteria (eg E. coli, P. aeruginosa, S. ...

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