New Efficient Route to. alpha.-Nitro Acids. Oxidation of Amino Acids with HOF. cntdot. CH3CN

S Rozen, A Bar-Haim, E Mishani

Index: Rozen, Shlomo; Bar-Haim, Arie; Mishani, Eyal Journal of Organic Chemistry, 1994 , vol. 59, # 5 p. 1208 - 1209

Full Text: HTML

Citation Number: 39

Abstract

The family of a-nitro acid derivatives is useful as a starting point for various reactions, and thus several synthetic methods have been devised for the preparation of its members. Most of these methods, however, are based on a combination of two fragments such as nitroacetate and an alkyl group or a carboxylic acid derivative and a nitro c0mpound. l These procedures are usually characterized by long reaction times with yields rarely exceeding ...