Arylaminoheterocycles. VI. Trisubstituted pyrimidines

MJ Langerman, CK Banks

Index: Langerman; Banks Journal of the American Chemical Society, 1951 , vol. 73, p. 3011

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Citation Number: 15

Abstract

As an extension of a previous investigation concerning 2-amino-4-arylaminopyrimidines2 it was considered of interest to prepare some trisubstituted pyrimidines which would be isosteric with several groups of symetrical triazines of pharmaceutical intere~ t.~*~ i~ For this purpose 2, 4, 6-trichloropyrimidine was chosen as the starting material. Barbituric acid has been converted to the trichloropyrimidines using phosphorus oxychloride in sealed tubes. ...