Synthesis and biological evaluation of curcumin analogues having a piperidone core as potential antioxidant agents

J Wang, G Sun, Z Li, W Mai, J Xie

Index: Wang, Jian; Sun, Gangchun; Li, Zhicheng; Mai, Wenpeng; Xie, Jingxi Journal of Chemical Research, 2012 , vol. 36, # 2 p. 63 - 65

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Abstract

A series of new unsymmetrical curcumin derivatives were designed and synthesised to which the indole fragment was introduced according to the principle of association. These compounds were characterised by 1H NMR, IR, ESIMS and elemental analysis and their antioxidant activity was investigated using the 1, 1-diphenyl-2-picrylhydrazyl method. The results indicated that curcumin analogues having a piperidone structure exhibit varying ...