Synthesis and cyclooxygenase-2 inhibiting property of 1, 5-diarylpyrazoles with substituted benzenesulfonamide moiety as pharmacophore: preparation of sodium salt …

M Pal, M Madan, S Padakanti…

Index: Journal of Medicinal Chemistry, , vol. 46, # 19 p. 3975 - 3984

Full Text: HTML

Citation Number: 54

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The diarylpyrazoles listed in Table 1 were synthesized according to Schemes 1−3. The arylhydrazine hydrochloride 25, a key intermediate for the synthesis of most of the ...