α??Boryl Isocyanides Enable Facile Preparation of Bioactive Boropeptides
A Zajdlik, Z Wang, JL Hickey, A Aman…
Index: Zajdlik, Adam; Wang, Zezhou; Hickey, Jennifer L.; Aman, Ahmed; Schimmer, Aaron D.; Yudin, Andrei K. Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8411 - 8415 Angew. Chem., 2013 , vol. 125, # 32 p. 8569 - 8573
Full Text: HTML
Citation Number: 28
Abstract
Boronic acids and their derivatives have found utility as synthetic building blocks,[1] chemosensors,[2] and as biologically active targets of synthesis.[3] Both the biological activity and chemical reactivity of boronic acids stem from boron s Lewis acidity. While useful in a broad range of applications, boron s propensity to undergo reactions with Lewis bases becomes problematic for functional-group compatibility during synthesis. Reagents that ...
Related Articles:
[Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K. Synthesis, 2004 , # 16 p. 2645 - 2652]
Aerobic Copper-Catalyzed O-Methylation with Methylboronic Acid
[Popovic, Stanimir; Bieraeugel, Hans; Detz, Remko J.; Kluwer, Alexander M.; Koole, Jelmer A. A.; Streefkerk, Dieuwertje E.; Hiemstra, Henk; Van Maarseveen, Jan H. Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16934 - 16937]
[Gewehr, Markus; Kunz, Horst Synthesis, 1997 , # 12 p. 1499 - 1510]