Synthesis and Separation of L-Trytophan Oligo-Peptides Assisted by Phosphorus Oxychloride

…, D Zhao, H Ren, K Lu, Y Zhao

Index: Ma, Li; Zhao, Dong-Xin; Ren, Hai-Ping; Lu, Kui; Zhao, Yu-Fen Asian Journal of Chemistry, 2010 , vol. 22, # 6 p. 4393 - 4397

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Abstract

Abstract With the assistance of inorganic phosphorus, a-amino acids could self-assemble into a series of oligopeptides, so it could provide a new route to synthesize peptides. In this paper, the self-assembly reaction of L-trytophan mediated by phosphorus oxychloride was monitored by using ESI-MS. The proper condition of the self-assembly reaction of L-Try was reported. The reaction products were purified by RP-HPLC and the fragmentation pathway ...