The Carbonylation and Hydroformylation Reactions with Certain Indole Derivatives1

JT Shaw, FT Tyson

Index: Shaw; Tyson Journal of the American Chemical Society, 1956 , vol. 78, p. 2538

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Citation Number: 13

Abstract

The reaction of carbon monoxide at elevated pressures and temperatures with the S- potassium salts of various 2-and 3-substituted indole derivatives has been investigated. The results indicate that the indole carbonylation reaction, as it is termed, can be used to prepare 3-indolecarboxaldehydes provided the 2-position is not too hindered sterically or substituted with electron-withdrawing groups. A new compound, N-formylindoline was prepared and ...