Tetrahedron

Palladium-catalyzed synthesis of quinoxaline derivatives

JM Wallace, BCG Söderberg, J Tamariz, NG Akhmedov…

Index: Wallace, Jeffery M.; Soederberg, Bjoern C.G.; Tamariz, Joaquin; Akhmedov, Novruz G.; Hurley, Mathew T. Tetrahedron, 2008 , vol. 64, # 41 p. 9675 - 9684

Full Text: HTML

Citation Number: 15

Abstract

A palladium-catalyzed reductive N-heteroannulation of enamines derived from 2- nitrobenzenamines forming mixtures of 1, 2-dihydroquinoxalines and 3, 4-dihydroquinoxalin- 2-ones is described. The reactions are performed using bis (dibenzylideneacetone) palladium (0), 1, 3-bis (diphenylphosphino) propane, and 1, 10-phenanthroline in DMF under 6atm of carbon monoxide at 70° C.

Related Articles:

Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284

[Conda-Sheridan, Martin; Marler, Laura; Park, Eun-Jung; Kondratyuk, Tamara P.; Jermihov, Katherine; Mesecar, Andrew D.; Pezzuto, John M.; Asolkar, Ratnakar N.; Fenical, William; Cushman, Mark Journal of Medicinal Chemistry, 2010 , vol. 53, # 24 p. 8688 - 8699]

Acid-Responsive Fluorescent Compounds Based on Nitro-Group-Substituted L-Shaped Pentacycles, Pyrrolo [1, 2-a][1, 8] naphthylidines

[Shoker, Tharallah A.; Ghattass, Khaled I.; Fettinger, James C.; Kurth, Mark J.; Haddadin, Makhluf J. Organic Letters, 2012 , vol. 14, # 14 p. 3704 - 3707]

Phenazine antibiotic inspired discovery of potent bromophenazine antibacterial agents against Staphylococcus aureus and Staphylococcus epidermidis

[Borrero, Nicholas V.; Bai, Fang; Perez, Cristian; Duong, Benjamin Q.; Rocca, James R.; Jin, Shouguang; Huigens Iii, Robert W. Organic and Biomolecular Chemistry, 2014 , vol. 12, # 6 p. 881 - 886]

Acid-Responsive Fluorescent Compounds Based on Nitro-Group-Substituted L-Shaped Pentacycles, Pyrrolo [1, 2-a][1, 8] naphthylidines

[Shoker, Tharallah A.; Ghattass, Khaled I.; Fettinger, James C.; Kurth, Mark J.; Haddadin, Makhluf J. Organic Letters, 2012 , vol. 14, # 14 p. 3704 - 3707]

Acid-Responsive Fluorescent Compounds Based on Nitro-Group-Substituted L-Shaped Pentacycles, Pyrrolo [1, 2-a][1, 8] naphthylidines

[Shoker, Tharallah A.; Ghattass, Khaled I.; Fettinger, James C.; Kurth, Mark J.; Haddadin, Makhluf J. Organic Letters, 2012 , vol. 14, # 14 p. 3704 - 3707]

More Articles...