Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists
RC Young, RC Mitchell, TH Brown…
Index: Journal of Medicinal Chemistry, , vol. 31, # 3 p. 656 - 671
Full Text: HTML
Citation Number: 472
Abstract
... (24) Fujisawa Pharmaceutical Co. Ltd. Jpn. ... Table I. Physicochemical Properties and Brain-Penetration Data for Three Hz Antagonists and Three Compounds That Readily Cross the Blood-Brain Barrier Journal of Medicinal Chemistry, 1988, Vol. 31, No. 3 659 log pn ...
Related Articles:
Palladium on charcoal-catalyzed ligand-free Stille coupling
[Yabe, Yuki; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao Tetrahedron, 2010 , vol. 66, # 45 p. 8654 - 8660]