A one-pot, three-component synthesis of thiazolidine-2-thiones
A Ziyaei-Halimehjani, K Marjani, A Ashouri
Index: Ziyaei-Halimehjani, Azim; Marjani, Katayoun; Ashouri, Akram Tetrahedron Letters, 2012 , vol. 53, # 27 p. 3490 - 3492
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Citation Number: 15
Abstract
An efficient method for the synthesis of thiazolidine-2-thiones is described via regiospecific iodocyclization of an allyl amine, carbon disulfide, and iodine. Dehydrohalogenation of the iodo-derivatives gives thiazole-2 (3H)-thiones. In addition, nucleophilic substitution of the iodine in the products is accomplished using NaN3, thiophenol, or dithiocarbamate.
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