Molecules

Non-Classical Transformation of Benzendiazonium Hydrogen Sulfates. Access to 1, 3-Dimethylisochromeno [4, 3-c] pyrazol-5 (1H)-one, a Potential …

B Maggio, D Raffa, MV Raimondi, G Daidone

Index: Maggio, Benedetta; Raffa, Demetrio; Raimondi, Maria Valeria; Daidone, Giuseppe Molecules, 2013 , vol. 18, # 10 p. 13096 - 13110

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Citation Number: 3

Abstract

Abstract: The compound 2-((1, 3-dimethyl-1 H-pyrazol-5-yl)(methyl) carbamoyl) benzene- diazonium hydrogen sulfate (10) was reacted with copper sulfate and sodium chloride, in the presence of ascorbic acid as reducing agent, to afford a mixture of the chlorinated epimers 4′-chloro-2, 2′, 5′-trimethyl-2′, 4′-dihydrospiro [isoindoline-1, 3′-pyrazol]-3-one (18) and (19), the epimers 4′-hydroxy-2, 2′, 5′-trimethyl-2′, 4′-dihydrospiro [isoindoline- ...