Synthesis of 3??(2??benzothiazolylthio) propanenitrile and related products

JJ D'Amico, L Suba, PG Ruminski

Index: D'Amico, John J.; Suba, Lydia; Ruminski, Peter G. Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 1629 - 1635

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Citation Number: 2

Abstract

Abstract The reaction of 2-mercaptobenzothiazole, 2-mercaptobenzoxazole or 5-chloro-2- mercaptobenzothiazole with either acrylonitrile or acrylamide under basic conditions afforded the N-cyanoethylated products 1, 2 and 3 or the N-amidoethylated products 4, 5 and 6, respectively. The reaction of the sodium salts of the same thiazolethiols with 3- chloropropionitrile furnished a mixture containing the N-cyanoethylated products 1, 2 and ...