Synlett

Synthesis of (+)-Kuraramine

F Frigerio, CA Haseler, T Gallagher

Index: Frigerio, Fabio; Haseler, Claire A.; Gallagher, Timothy Synlett, 2010 , # 5 p. 729 - 730

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Citation Number: 3

Abstract

Abstract The first synthesis of (+)-kuraramine via oxidative cleavage of (-)-N-methylcytisine is reported. An alternative but unsuccessful approach to (+)-kuraramine is also described based on extending an intramolecular enolate addition protocol that had previously been applied successfully to cytisine.