Studies on Antibiotics and Related Substances. XII. Syntheses of 10-Oxo-11-dodecenoic Acid and 11-Oxo-12-tridecenoic Acid, Antitumor Substances

M Kinoshita, S Umezawa

Index: Kinoshita,M.; Umezawa,S. Bulletin of the Chemical Society of Japan, 1961 , vol. 34, p. 308 - 312

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Citation Number: 3

Abstract

1) 11-Oxo-12-tridecenoic acid (IXa) has been prepared from ethyl 9-bromononanoate (II) via 11-oxododecanoic acid (IVa) and the corresponding Mannich base Va. 2) 10-Oxo-11- dodecenoic acid (IXb) has been prepared from 10-oxoundecanoic acid (IVb) via the corresponding Mannich base Vb. 3) It has been found that IXa and IXb possess antitumor and antifugal activities.