Comparative metabolism of cinobufagin in liver microsomes from mouse, rat, dog, minipig, monkey, and human

XC Ma, J Ning, GB Ge, SC Liang, XL Wang…

Index: Drug Metabolism and Disposition, , vol. 39, # 4 p. 675 - 682

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Citation Number: 40

Abstract

... Because CB is a substrate of CYP3A, more adverse drug-drug reactions or undesirable effects may occur when CB is coadministrated with drugs that are ... and endogenous steroids could cause marked modifications in CYP3A-mediated metabolism (Nakamura et al ...