Journal of the Chinese Chemical Society

Synthesis of deuterium labeled tryptamine derivatives

YY Wang, C Chen

Index: Wang, Yu-Yun; Chen, Chinpiao Journal of the Chinese Chemical Society, 2007 , vol. 54, # 5 p. 1363 - 1368

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Citation Number: 10

Abstract

Abstract The synthesis of deuterium labeled tryptamine derivatives,[2-(1H-indol-3-yl)-[2 H 4]- ethyl]-dimethylamine (DMT),[2 H 10]-diethyl-[2-(1H-indol-3-yl)-ethyl]-amine (DET),[2-(1H- indol-3-yl)-ethyl]-[2 H 6]-dipropyl-amine (DPT) and [2 H 2]-alpha-methyltryptamine (AMT) is described. The isotopically labeled compounds are used as internal standards in gas chromatography-mass spectrometry (GC-MS) assays.