Synthesis and antimicrobial activities of new 1, 4-benzothiazines possessing thiazolyl/imidazolyl moieties

…, VS Ingle, RV Dengle, SP Bondge, RA Mane

Index: Bhingolikar; Ingle; Dengle; Bondge; Mane Journal of the Indian Chemical Society, 2002 , vol. 79, # 8 p. 703 - 704

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Abstract

Résumé/Abstract 3-[4'-Methyl-2'-(4'-substituted-phenyl) thiazol-5'-yl]-1, 4-benzothiazine hydrobromides (3A) and 3-[1'-(4"-substituted-phenyl)-2'-mercapto-4'-imidazol-5'-yl]-1, 4- benzothiazine hydrobromides (3B) were synthesized. 5-Acyl-4-methylthiazoles (1A) and 5- acyl-2-mercapto-4-methylimidazoles (1B) were brominated using phenyltrimethylammonium tribromide as selective brominating agent to obtain the corresponding bromoacyl products ...