Approaches to sesquiterpenes containing three contiguous quaternary carbon atoms. Synthesis of 3-methoxythapsene

A Srikrishna, DB Ramachary

Index: Srikrishna; Ramachary Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 4 p. 751 - 761

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Citation Number: 6

Abstract

Abstract: Synthetic approach to 3-alkoxythapsane, comprising of the carbon framework of a small group of sesquiterpenes containing three contiguous quaternary carbon atoms has been described. A combination of alkylation, orthoester Claisen rearrangement and intramolecular diazoketone cyclopropanation has been employed for the creation of the three requisite contiguous quaternary carbon atoms.