Tetrahedron letters

Implementation of a combinatorial cleavage and deprotection scheme. 1. Synthesis of phthalhydrazide libraries

J Nielsen, PH Rasmussen

Index: Nielsen, John; Rasmussen, Palle H. Tetrahedron Letters, 1996 , vol. 37, # 19 p. 3351 - 3354

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Citation Number: 19

Abstract

Phthalhydrazide libraries are synthesized in solution from substituted hydrazines and phthalimides in several different library formats including single compounds, indexed sub- libraries and a full library. When carried out during solid-phase synthesis, this combinatorial cleavage and deprotection scheme offers the possibility for generating a diverse library of substituted phthalhydrazides.