Synthesis and metabotropic glutamate receptor activity of S-oxidized variants of (-)-4-amino-2-thiabicyclo-[3.1. 0] hexane-4, 6-dicarboxylate: identification of potent, …
JA Monn, SM Massey, MJ Valli, SS Henry…
Index: Journal of Medicinal Chemistry, , vol. 50, # 2 p. 233 - 240
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Citation Number: 51
Abstract
... Journal of Medicinal Chemistry. ... Results. Chemistry. Analogs (−)-10, (+)-11, and (−)-12 were prepared as described in the Scheme from the mGlu2/3 receptor-active (−)-1R,4S,5S,6S enantiomer (−)-3, itself synthesized as previously described. ...
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