1, 2??Addition of α, α, α??Trichlorotoluene to Ketones via a Mg Barbier Reaction in DMF: New Route to Cycloalk??1??en??1??yl and Alk??1??en??1??yl Phenyl Ketones

A Aaziz, S Oudeyer, E Léonel, JP Paugam…

Index: Aaziz, Akima; Oudeyer, Sylvain; Leonel, Eric; Paugam, Jean Paul; Nedelec, Jean-Yves Synthetic Communications, 2007 , vol. 37, # 7 p. 1147 - 1154

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Abstract

View all references in 1922, has been frequently investigated thereafter to improve the yields in α,β??unsaturated ketones, which are no more than 65%.2–15 View all references More recently, 1??benzoylcyclopentene was prepared as the major regioisomer by a palladium??catalyzed cross??carbonylation of phenyl iodide with cyclopentene.1616. Satoh , T. , Itaya , T. , Okuro , K. , Miura , M. and Nomura , M. 1995. Palladium??catalyzed cross??carbonylation of aryl ...

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