Tetrahedron

An efficient stereoselective synthesis of 1α, 24 (R)-dihydroxyvitamin D 3 by the dienyne route

Y Fall, M Torneiro, L Castedo, A Mouriño

Index: Fall, Yagamare; Torneiro, Mercedes; Castedo, Luis; Mourino, Antonio Tetrahedron, 1997 ,  vol. 53,  # 13  p. 4703 - 4714

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Citation Number: 18

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Dedicated to the memory of Prof. Ignacio Ribas. ... 1α,24(R)-Dihydroxyvitamin D 3 (5e) was synthesized. The key step in the preparation of the side-chain was opening of the chiral epoxide 10 by the α-anion of the nitrile 9. The triene system was synthesized by the dienyne route.