The Journal of organic chemistry
Synthesis of Oligomers Derived from Amide-Linked Neuraminic Acid Analogues#
TQ Gregar, J Gervay-Hague
Index: Gregar, Travis Q.; Gervay-Hague, Jacquelyn Journal of Organic Chemistry, 2004 , vol. 69, # 4 p. 1001 - 1009
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Citation Number: 46
Abstract
N-Fluoren-9-ylmethoxycarbonyl-protected sugar amino acids derived from α-O-methoxy-and 2, 3-dehydroneuraminic acids have been prepared. Incorporation of these monomer units into solid-phase synthesis led to the efficient synthesis of two series of oligomers varying from one to eight units in length. The (1→ 5)-linked amides of 2, 3-dehydroneuraminic acid were further subjected to hydrogenation giving a third series of oligomers with a β-hydrido ...