Synthesis of 1, 3-diynes in the purine, pyrimidine, 1, 3, 5-triazine and acridine series

WE Lindsell, C Murray, PN Preston, TAJ Woodman

Index: Edward Lindsell; Murray, Christopher; Preston, Peter N.; Woodman, Thomas A. J. Tetrahedron, 2000 , vol. 56, # 9 p. 1233 - 1245

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Citation Number: 61

Abstract

A range of conjugated 1, 3-diynes, R1C CC CR2, has been prepared that incorporate the following heteroaromatic units as head groups of the substituents R1 and/or R2: pyrimidinyl, purinyl, 2, 4-diamino-1, 3, 5-triazinyl and acridinyl. Compounds containing the first three groups as terminal heterocyclic substituents in both R1 and R2 are bonded through methylene linkers {(CH2) n, n= 1, 4 or 9} to the 1, 3-diyne; also reported are amphiphilic ...