Efficient Synthesis of 1, 2-Dicyclopropylethyne and (Cyclopropylethynyl) cyclobutane from 1, 2-Di-(ω-haloalkyl) ethynes and 1-Cycloalkyl-2-(ω-haloalkyl) ethynes

SC Suri, JC Marcischak

Index: Suri, Suresh C.; Marcischak, Jacob C. Organic Preparations and Procedures International, 2013 , vol. 45, # 2 p. 154 - 161

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Abstract

The classical methods for the synthesis of alkynes involve the alkynylation of alkyl halides with metal acetylides1 as well as the base-promoted dehydrohalogenation2 of vicinal dihalide/vinyl halide. Our research interest is directed toward the synthesis of 1, 2- cyclopropyl-and/or cyclobutylalkynes which can be achieved either by generation of the acetylene bond from an appropriate precursor with dicycloalkyl substituents or by the ...