Tetrahedron Letters

Novel preparation of functionalized iodotetrahydronaphthyridine, iodoazaindoline, and iodotetrahydropyridoazepine systems

HN Nguyen, ZJ Wang

Index: Nguyen, Hanh Nho; Wang, Zhan J. Tetrahedron Letters, 2007 , vol. 48, # 42 p. 7460 - 7463

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Citation Number: 11

Abstract

A novel method, which utilizes a key halogen dance step for the preparation of iodotetrahydronaphthyridine, iodoazaindoline, and iodotetrahydropyridoazepine ring- systems is described. A variety of transformations of the iodo-functional group are also reported to demonstrate the utility of this method.