Allosteric interaction of metal ions with saccharides in a crowned diboronic acid

G Deng, TD James, S Shinkai

Index: Deng, Gang; James, Tony D.; Shinkai, Seiji Journal of the American Chemical Society, 1994 , vol. 116, # 11 p. 4567 - 4572

Full Text: HTML

Citation Number: 93

Abstract

Abstract: A diboronic acid saccharide (covalent) receptor site and a crown metal ion (electrostatic) receptor site are succesfully coupled in an allosteric system. The binding of monosaccharides with 2b as intramolecular 1: 1 complexes was monitored bv circular dichroism (CD). Added calcium perchlorate reduces the binding of the 1: l saccharide complexes as follbwed by a decrease in the'CD activity. the Na+/D-glucose cotransport ...