Substitution and ring closure reactions of phthalazine derivatives

…, HA El??Sherief, GM El??Naggar…

Index: Badr, M. Z. A.; El-Sherief, H. A.; El-Naggar, G. M.; Mahgoub, S. A. Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 471 - 475

Full Text: HTML

Citation Number: 13

Abstract

Abstract 1-(Phenylthio)-and 1-(hydroxycarbonylmethylthio)-4-methylphthalazines were prepared from 1-chloro-4-methylphthalazines (1). A series of 2-benzyl-and benzenesulphonyl derivatives was prepared from the corresponding halides and 4-methyl-1 (2H)-phthalazinone (4). 4-Methyl-1 (2H)-phthalazinthione (6) was substituted at SH group to give 1-(benzylthio)-and 1-(ethoxycarbonylmethylthio)-4-methylphthalazines, 7 and 8 ...