Reduction of. beta.-keto sulfoxides: a highly efficient asymmetric synthesis of both enantiomers of allylic alcohols

G Solladie, G Demailly, C Greck

Index: Solladie, Guy; Demailly, Gilles; Greck, Christine Journal of Organic Chemistry, 1985 , vol. 50, # 9 p. 1552 - 1554

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Citation Number: 120

Abstract

From the imidazole. From the ester. competitive 1, 4 addition was observed at-78" C. However, when the reaction was conducted at 0" C, less than 10% of 1, 4 addition was detected (Scheme 11, Table I). Finally, in using, instead of the ester, the corresponding imidazole, pure 1, 2 addition was obtained at-78" C. Several a,@-unsaturated@-keto sulfoxides were prepared either from the corresponding esters at 0" C or from the ...